我是实验室个人介绍2
Yu Jiang Dr. Yu Jiang

Professional Title: Professor and PI of Agriculture Genomics Lab
Research Field: Agriculture Genomics
Date of Birth: Dec. 1983
Cell phone: +86 15029266711
Email: jiangyu96@163.com; yu.jiang@nwafu.edu.cn
Address: College of Animal Science and Technology,
Northwest A & F University, Yangling, China, 712100

EDUCATION and WORKING 2015 - present     Professor in College of Animal Science and Technology, Northwest A&F University
2013 - 2015        Associate Professor in College of Animal Science and Technology, Northwest A&F University
2011 - 2013        Postdoctoral Fellow- Genome Sequence Analyst, CSIRO Livestock Industries
2006 - 2011        Ph.D., State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, CAS, China
2002 - 2006        B.Sc. of Biotechnology, College of Life Science, Fudan University, China

RESEARCH INTERESTS We analyzed the big agricultural omics data and identified some major genomic signatures associated with interactions between diet, the digestive system, and metabolism in ruminants, and managed to discover the key economic genotype-phenotype association in Peking duck with one mutation increased body size by 15% and feed efficiency by 6%. Through innovative bioinformatics analysis, we first reported the use of optical mapping profiling for animal genome assembly and GWAS analysis using structural variations. We also contributed to the deciphering of the genetic heritage of worldwide cattle from five distinct pedigrees, and revealed a series of adaptive evolutions. We have published 12 manuscripts as first or senior authorship in journals such as Science, Nature Biotechnology, Nature Communications, and Cell Research. Our current major area of interest is focused on ruminant livestock and their foregut fermentation system, the rumen, which represents the world’s extraordinarily efficient stomach using microbial flora to ferment the feed. We try to reveal the genetic basis of the rumen and its microbial ecosystem, and finally develop a bionic machine of artificial rumen combined with milk reactor as facilitating the conversion of lignocellulose-rich plant materials, of low value in the human diet, to high value animal protein and lipid.

GRANTS

  1. PI of Hundred Talents Program in Shaanxi province, ¥ 0.5 million, funded by Shaanxi province, China (2015-2016)
  2. PI of the project "Evolutionary genomics analysis in Oula-type Tibetan sheep: finding the genes underlying high-altitude adaptation", ¥ 0.77 million , funded by the National Natural Science Foundation of China (2016-2019)
  3. PI of the project "The Pan Caprinae Genome Plan", ¥ 6 million, funded by "Thousand Youth Talents Plan" and Northwest A & F University (2016-2020)
  4. PI of Outstanding young training Fellowship, ¥ 0.4 million, funded by Northwest A & F University, China (2015-2017)
  5. PI of Talent Start up Funds, ¥ 0.5 million, funded by Northwest A & F University, China (2014-2016)

AWARDS

PUBLICATIONS Main contributed papers (# first author, *corresponding author)

  1. Li D#, Dong Y#, Jiang Y#, Jiang HF#, Cai J, Wang W*, A de novo originated gene depresses budding yeast mating pathway and is repressed by the protein encoded by its antisense strand. Cell Research 20(4)(2010),408-420.
  2. Jiang Y#, Li Y#, Lee W#, Xu X, Zhang Y, Zhao R, Zhang Y*, Wang W*, Venom gland transcriptomes of two elapid snakes (Bungarus multicinctus and Naja atra) and evolution of toxin genes. BMC Genomics 12(1) (2011), 1-13.
  3. Dong Y#, Xie M#, Jiang Y#…, Wang J*, Wang W*, Sequencing and automated whole-genome optical mapping of the genome of a domestic goat. Nature Biotechnology 31(2) (2013): 135-141 (ESI Highly Cited Papers).
  4. Jiang Y#, Xie M#, Chen W#…, Wang W*, Dalrymple B*. 2014. The sheep genome illuminates biology of the rumen and lipid metabolism. Science 344 (2014): 1168-1172. (ESI Highly Cited Papers).
  5. Zhou Z#, Jiang Y#, Wang Z#…, Wang W*, Tian Z*. Resequencing 302 wild and cultivated accessions identifies genes related to domestication and improvement in soybean. Nature biotechnology 23(4) (2015): 408-414 (ESI Highly Cited Papers).
  6. Jiang Y#, Wang X#, Kijas J, Dalrymple B*. Beta globin gene evolution in the ruminants: evidence for an ancient origin of sheep haplotype B. Animal Genetics (2015) 46: 506–514.
  7. Dong Y#, Zhang X#, Xie M#…, Wang W*, Jiang Y* Reference genome of wild goat (Capra aegagrus) and sequencing of goat breeds provide insight into genic basis of goat domestication. BMC Genomics (2015), 16:431.
  8. Chen H, Jiang Y*, Progress and Prospects in Domestic Animals and Breeding: a Review of Genomic Copy Number Variations. Biotechnology Bulletin (2015) 31(11): 35-42.
  9. #Li M, #Zhou H, #Pan X, …, Zi X*, Jiang Y*, Cassava foliage affects the microbial diversity of Chinese indigenous geese caecum using 16S rRNA sequencing[J]. Scientific Reports, 2017, 7.
  10. Wang X, Zheng Z, Cai Y, Chen T, Li C, Fu W, Jiang Y*. CNVcaller: Highly Efficient and Widely Applicable Software for Detecting Copy Number Variations in Large Populations. GigaScience, 2017.12.4, 6(12)
  11. #Chen N, #Cai Y, #Chen Q,..., Jiang Y*, Lei C*. Whole-genome resequencing reveals world-wide ancestry and multiple adaptive introgression events of domesticated cattle in East Asia. Accepted by Nature communications (2018)
  12. #Zhou Z, #Li M, #Cheng H,...,  Hou S*, Jiang Y*. An intercross population study reveals genes associated with body size and plumage color in ducks. Accepted by Nature communications (2018)

PRESENTATIONS Invited presentations in international conferences

  1. "The progress of sheep and goat genome assembly" May 13-14, 2010, Shenzhen, China."
    International Conference of 1000 Plant and Animal Reference Genomes Project
  2. "Sequencing and assembly of the sheep reference genome".
    Plant & Animal Genomes XIX Conference,
    Jan 15-19, 2011 San Diego, US.
  3. "High-Resolution Analysis of Allelic Expression in Seven Sheep tissues".
    Plant & Animal Genomes XIX Conference,
    Jan 15-19, 2011 San Diego, US.
  4. "Sheep Genome Project: Gap Filling and Unbalanced Allelic Expression".
    Plant & Animal Genomes XX Conference,
    Jan 14-18, 2012 San Diego, US.
  5. "The quality of sheep reference genome, OAR v3.1".
    5th 3SR Consortium Meeting,
    June 28-29, Alghero, Italy.
  6. "A reference genome of the domestic goat".
    33rd International Society for Animal Genetics,
    July 15-20, 2012, Cairns, Australia.
  7. "The imprintome of a domestic sheep".
    33rd International Society for Animal Genetics,
    July 15-20, 2012, Cairns, Australia.
  8. "The domestic sheep reference genome assembly".
    33rd International Society for Animal Genetics,
    July 15-20, 2012, Cairns, Australia.
  9. "Detection of large-scale variation among sheep goat and cattle genomes".
    34th International Society for Animal Genetics,
    July 27-31, 2014, Xi'an, China.
  10. "Comparative genomics analysis provides new insights to ruminant biology".
    9th International Conference on Genomics,
    Sep 9-12, 2014, Shenzhen, China.
  11. "Construction and evaluation of the Caprinae Pan-genome".
    3rd Livestock genomics meeting,
    Sep 14-16, 2016, Cambridge, UK.
  12. “The ruminant biology and evolution revealed by a flock of ruminant de novo genomes”
    36th International Society for Animal Genetics,
    July 17-21, 2017, Dublin, Ireland
  13. “world-wide ancestry and multiple adaptive introgression events of domesticated cattle”
    Fossils and Ancient Genomics Symposium,
    Apr 17, 2018, Shenzhen, China